Fig. 1 · Structure
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1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine
Phospholipid
1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that incorporates into lipid monolayers and small unilamellar vesicles. This compound is utilized in the formulation of endoplasmic reticulum-targeted liposomes (PERLs), when combined in a specific molar ratio with other phospholipids. Research indicates that PERLs can significantly diminish cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and suppress HIV-1 particle secretion from HIV-1-infected PBMCs, making it valuable for studies in cellular metabolism and viral research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 99296-81-8 |
| Applications | Phospholipid |
| Formula | C52H80NO8P |
| Molecular Weight | 878.17 |
| SMILES | CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(O[C@H](COC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.