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1,2-DLPC-d46

Catalog No.: B14124
Stable Isotope
1,2-DLPC-d46 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d46) is a deuterium-labeled variant of 1,2-DLPC, which serves as a ligand for LRH-1 agonists. This phospholipid is integral to liposome synthesis and promotes lipolysis and apoptosis in adipocytes via a TNFα-dependent pathway. Additionally, 1,2-DLPC-d46 has been shown to mitigate palmitate-induced insulin resistance in myocytes through PPARα-mediated anti-inflammatory effects, making it a valuable tool for various metabolic research applications.
1,2-DLPC-d46 136565-60-1 Stable Isotope
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description1,2-DLPC-d46 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d46) is a deuterium-labeled variant of 1,2-DLPC, which serves as a ligand for LRH-1 agonists. This phospholipid is integral to liposome synthesis and promotes lipolysis and apoptosis in adipocytes via a TNFα-dependent pathway. Additionally, 1,2-DLPC-d46 has been shown to mitigate palmitate-induced insulin resistance in myocytes through PPARα-mediated anti-inflammatory effects, making it a valuable tool for various metabolic research applications.
Product Information
Catalog NumB14124
FormulaC32H18D46NO8P
Molecular Weight668.11
CAS Number136565-60-1
SMILESO=C(O[C@@H](COP([O-])(OCC[N+](C)(C)C)=O)COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
Synonyms1,2-Dilauroyl-sn-glycero-3-phosphocholine-d46
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