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1-(3,3-Difluoro-4-piperidinyl)piperazine

PROTAC Linker

1-(3,3-Difluoro-4-piperidinyl)piperazine functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in synthesizing PROTACs for targeted protein degradation research, enabling studies on protein function and therapeutic interventions. Its unique structure enhances binding affinity and selectivity for target proteins, making it a valuable tool in chemical biology and drug discovery.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2168258-10-2
Applications	PROTAC Linker
Formula	C₉H₁₇F₂N₃
Molecular Weight	205.25
SMILES	FC1(F)CNCCC1N2CCNCC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.