Fig. 1 · Structure
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1-3-(4-tert-Butylbenzoyl)propyl-4-hydroxypiperidine
Ebastine Intermediate
1-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine serves as an important intermediate in the synthesis of Ebastine, a potent second-generation histamine H1 receptor antagonist. Ebastine is primarily utilized in the research of allergic rhinitis and chronic idiopathic urticaria, demonstrating effective alleviation of allergy-related symptoms. This compound is essential for the development and study of therapeutics targeting histamine-related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 97928-18-2 |
| Applications | Ebastine Intermediate |
| Formula | C19H29NO2 |
| Molecular Weight | 303.44 |
| SMILES | O=C(CCCN1CCC(CC1)O)C2=CC=C(C(C)(C)C)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.