Fig. 1 · Structure

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1,4-Di(3-hydroxypropoxy)butane

PROTAC Linker

1,4-Di(3-hydroxypropoxy)butane serves as a linker in the development of PROTAC molecules, specifically in the synthesis of the Aster-A degrader-1. This compound enables the targeted degradation of proteins by facilitating the formation of an E3 ligase complex. Its application is crucial for researchers exploring targeted protein degradation and therapeutic strategies in cancer and other diseases.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2052305-98-1
Applications PROTAC Linker
Formula C10H22O4
Molecular Weight 206.28
SMILES
OCCCOCCCCOCCCO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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