Fig. 1 · Structure

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1-(4-Nitrophenyl)piperazine

Piperazine Linker

1-(4-Nitrophenyl)piperazine is a versatile piperazine linker that facilitates the synthesis of HDAC3/6 inhibitors, specifically HDAC3/6-IN-2, which is an anti-cancer agent. This compound enables the coupling of CDODA-Me and Vorinostat, enhancing their pharmacological properties for cancer research. Its application in drug development is pivotal for studies focused on histone deacetylase inhibition and targeted cancer therapy.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 6269-89-2
Applications Piperazine Linker
Formula C10H13N3O2
Molecular Weight 207.23
SMILES
O=[N+](C1=CC=C(N2CCNCC2)C=C1)[O-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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