Fig. 1 · Structure
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1,9-Dimethylmethylene blue
Photosensitizer
1,9-Dimethylmethylene blue is a photosensitizer that generates reactive oxygen species, including singlet oxygen, upon activation. This compound is effective for photoinactivating viruses such as the R17 phage and vesicular stomatitis virus, and it oxidizes hemoglobin through non-singlet oxygen pathways. Its monomeric form exhibits a higher affinity for nucleic acids, allowing for virus inactivation without the formation of methemoglobin under specific conditions. Additionally, it interacts with glycosaminoglycans, leading to observable color changes, and is applicable in spectrophotometric analyses for glycosaminoglycan quantification. Its diverse photochemical and binding characteristics make it valuable for research in viral infections and related biochemical studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 23481-50-7 |
| Applications | Photosensitizer |
| Formula | C18H22ClN3S |
| Molecular Weight | 347.91 |
| SMILES | CC1=CC(N(C)C)=CC2=[S+]C(C=C(N(C)C)C=C3C)=C3N=C12.[Cl-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.