Fig. 1 · Structure

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1-Methylcytosine

Pyrimidinone

1-Methylcytosine is a pyrimidinone that functions as a nucleobase in hachimoji DNA, pairing specifically with isoguanine. This compound exhibits weak antiproliferative activity against cervical cancer cells, making it a valuable tool for cancer research. Its unique properties facilitate studies in nucleic acid chemistry and the exploration of alternative genetic systems in oncological applications.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1122-47-0
Applications Pyrimidinone
Formula C5H7N3O
Molecular Weight 125.13
SMILES
NC(C=CN1C)=NC1=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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