Fig. 1 · Structure
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1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine
Phospholipids
1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine, also known as 14:0 Lyso PE, is a lysophospholipid that features a phosphoethanolamine headgroup and a myristoyl fatty acid tail. This compound plays a critical role in cell signaling, known to induce transient increases in intracellular calcium levels in PC12 cells. Research indicates that elevated serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are associated with malignant breast cancer, highlighting its potential as a biomarker in cancer research. Its free amine group also allows for functionalization through conjugation with NHS-active esters or carboxylic acids using coupling agents.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 123060-40-2 |
| Applications | Phospholipids |
| Formula | C19H40NO7P |
| Molecular Weight | 425.50 |
| Synonyms | 14:0 Lyso PE; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine |
| SMILES | CCCCCCCCCCCCCC(OC[C@@H](O)COP(OCCN)(O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.