Fig. 1 · Structure
Documents & Downloads
1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine
Oxidized Phospholipid
1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine is an oxidized phospholipid that influences cellular viability and oxidative stress in human umbilical vein endothelial cells (HUVECs). This compound induces ferroptosis by promoting lipid peroxidation and superoxide anion production while reducing glutathione and GPX4 levels. It also enhances FABP3 expression and disrupts mitochondrial function, leading to apoptosis in aortic smooth muscle cells. Additionally, 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine activates caspase-11 and encourages IL-1β release from immune cells, making it a valuable tool for research on atherosclerosis and related pathways.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 89947-79-5 |
| Applications | Oxidized Phospholipid |
| Formula | C29H56NO10P |
| Molecular Weight | 609.73 |
| Synonyms | PGPC |
| SMILES | C[N+](C)(C)CCOP(OC[C@H](OC(CCCC(O)=O)=O)COC(CCCCCCCCCCCCCCC)=O)([O-])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.