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1-Stearoyl-sn-glycero-3-phosphocholine-d35

Catalog No.: A31409
Stable Isotope
1-Stearoyl-sn-glycero-3-phosphocholine-d35 is a deuterium-labeled variant of 1-Stearoyl-sn-glycero-3-phosphocholine, serving as a stable isotope for precision research applications. This lysophosphatidylcholine inhibits histone deacetylase 3 (HDAC3) activity and reduces phosphorylation of STAT3 in K562 cells. Additionally, it induces apoptosis and demonstrates anticancer properties specifically in chronic myelogenous leukemia (CML) K562 cells, making it valuable for studies in cancer biology and therapeutic development.
1-Stearoyl-sn-glycero-3-phosphocholine-d35 327178-92-7 Stable Isotope
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1mg
$625.00
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description1-Stearoyl-sn-glycero-3-phosphocholine-d35 is a deuterium-labeled variant of 1-Stearoyl-sn-glycero-3-phosphocholine, serving as a stable isotope for precision research applications. This lysophosphatidylcholine inhibits histone deacetylase 3 (HDAC3) activity and reduces phosphorylation of STAT3 in K562 cells. Additionally, it induces apoptosis and demonstrates anticancer properties specifically in chronic myelogenous leukemia (CML) K562 cells, making it valuable for studies in cancer biology and therapeutic development.
Product Information
Catalog NumA31409
FormulaC26H19D35NO7P
Molecular Weight558.90
CAS Number327178-92-7
SMILES[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C(OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O)=O
Synonyms18:0 Lyso-PC-d35; LPC(18:0)-d35
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Isotope-Labeled Compounds