HDAC3 | Adooq Bioscience

Cat. No.: A10246

CAS No.: 1012054-59-9

CUDC-101

CUDC-101 is a novel compound which inhibits multiple targets, which is designed to inhibit HDAC, EGFR and Her2.

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5 mg

$35.00

10 mg

$65.00

All 8 sizes

Cat. No.: A10764

CAS No.: 382180-17-8

Pyroxamide (NSC 696085)

Synonyms: NSC-696085

Pyroxamide (NSC 696085) is a potent inhibitor of affinity-purified HDAC1 and causes the accumulation of acetylated core histones in MEL cells cultured with the agent.

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5 mg

$35.00

10 mg

$65.00

All 6 sizes

Cat. No.: A11355

CAS No.: 251456-60-7

M344

Synonyms: Histone Deacetylase Inhibitor III,MS344

M344 is a potent inhibitor of HDAC with IC50 of 100 nM and able to induce cell differentiation.

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5 mg

$35.00

10 mg

$65.00

All 6 sizes

Cat. No.: A11361

CAS No.: 926259-99-6

BG45

BG45 is an HDAC class I inhibitor with selectivity for HDAC3 (IC50 = 289 nM). It inhibits HDAC1, HDAC2, and HDAC6 with greatly reduced potency (IC50s = 2, 2.2, and >20 μM, respectively).

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5 mg

$25.00

10 mg

$45.00

All 7 sizes

Cat. No.: A11940

CAS No.: 1316214-52-4

ACY-1215 (Rocilinostat)

Synonyms: ACY1215

ACY-1215 selectively targets and binds to HDAC6, thereby disrupting the Hsp90 protein chaperone system through hyperacetylation of Hsp90 and preventing the subsequent aggresomal protein degradation.

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5 mg

$20.00

10 mg

$35.00

All 5 sizes

Cat. No.: A11964

CAS No.: 112522-64-2

Tacedinaline (CI994)

Synonyms: CI-994; Acetyldinaline; Goe 5549; G? 5549. PD 123654

CI-994 is a histone deacetylase (HDAC) inhibitor and induces histone hyperacetylation in living cells.

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5 mg

$30.00

10 mg

$35.00

All 7 sizes

Cat. No.: A12511

CAS No.: 849234-64-6

BRD-6929

BRD-6929 (Cpd-60) is a brain-penetrant, selective inhibitor of HDAC1 and HDAC2 (IC50= 1 and 8 nM), extracted from patent US2018360927.

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1 mg

$20.00

5 mg

$35.00

All 8 sizes

Cat. No.: A12722

CAS No.: 287383-59-9

Scriptaid

Scriptaid is an HDAC inhibitor (histone deacetylase).

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5 mg

$55.00

10 mg

$90.00

All 7 sizes

Cat. No.: A13139

CAS No.: 1215493-56-3

RG2833 (RGFP109)

Synonyms: RGFP109

RG2833 ( is a brain-penetrant HDAC inhibitor with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3.

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5 mg

$25.00

10 mg

$45.00

All 8 sizes

Cat. No.: A14341

CAS No.: 1418033-25-6

LMK-235

LMK-235 is a selective histone deacetylase (HDAC) 4 and HDAC5 inhibitor.

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5 mg

$40.00

10 mg

$65.00

All 7 sizes

Cat. No.: A14354

CAS No.: 910462-43-0

Domatinostat (4SC-202)

Synonyms: 4SC-202

4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity.

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1 mg

$30.00

5 mg

$75.00

All 7 sizes

Cat. No.: A17861

CAS No.: 1616493-44-7

Tucidinostat (Chidamide)

Synonyms: HBI-8000; HBI8000 Chidamide; CS-055; Chidamide

Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 (IC50s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9.

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5 mg

$50.00

10 mg

$85.00

All 8 sizes

Cat. No.: A21126

CAS No.: 497833-27-9

Givinostat

Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively.

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5 mg

$90.00

10 mg

$160.00

All 5 sizes

Cat. No.: A24881

CAS No.: 83209-65-8

HC-Toxin

HC-Toxin is a potent histone deacetylase (HDAC) inhibitor with an IC50 of 30 nM. This cyclic tetrapeptide effectively induces apoptosis in tumor cells, demonstrating significant anticancer activity. Its mechanism of action makes it valuable for research in cancer therapy and the modulation of gene expression.

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All 3 sizes

Cat. No.: A26475

CAS No.: 1267502-34-0

FNDR-20123 free base

FNDR-20123 free base is a potent, orally active anti-malarial agent that functions as a histone deacetylase (HDAC) inhibitor. It demonstrates significant inhibitory activity against Plasmodium falciparum, achieving IC50 values of 41 nM during the asexual stage and 190 nM for male gametocytes. In addition, FNDR-20123 free base selectively inhibits various HDAC isoforms, including HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8, with respective IC50 values of 25 nM, 29 nM, 2 nM, 11 nM, and 282 nM. This compound is a valuable tool for research into the treatment of malaria and the role of HDACs in cellular regulation.

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Cat. No.: A12758

CAS No.: 1316215-12-9

Citarinostat (ACY-241)

Synonyms: HDAC-IN-2; ACY-241

ACY-241 is a new, selective and orally available inhibitor of HDAC6.

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1 mg

$35.00

5 mg

$90.00

All 7 sizes

Cat. No.: A11153

CAS No.: 1339928-25-4

Fimepinostat (CUDC-907)

Synonyms: CUDC907

CUDC-907 (Fimepinostat) is a single small molecule inhibitor that targets both PI3K and HDAC. CUDC-907 is more efficacious than either a single PI3K or HDAC inhibitor reference compound or a combination of the two single agents at maximally tolerated doses.

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2 mg

$30.00

5 mg

$55.00

All 8 sizes

Cat. No.: A10611

CAS No.: 209783-80-2

Entinostat (MS-275)

Synonyms: SNDX-275; MS-275

MS-275 (Entinostat) is a potent HDAC inhibitor with IC50 of 0.3 and 8uM for HDAC1 and HDAC3, respectively.

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5 mg

$30.00

10 mg

$35.00

All 7 sizes

Cat. No.: A11920

CAS No.: 128517-07-7

Romidepsin (FK228, Depsipeptide)

Synonyms: FK228; Depsipeptide

Romidepsin strongly inhibits HDAC1 and HDAC2 with IC5N/A of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6 with IC5N/A 25 nM and 79N/A nM, respectively.