Fig. 1 · Structure
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10-((2,5-Dioxopyrrolidin-1-yl)oxy)-10-oxodecanoic acid
PROTAC Linker
10-((2,5-Dioxopyrrolidin-1-yl)oxy)-10-oxodecanoic acid serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). By enabling the covalent connection between target proteins and E3 ligases, it enhances the efficacy of targeted protein degradation. This compound is essential for researchers focused on studying protein regulation and therapeutic development in disease models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 159350-38-6 |
| Applications | PROTAC Linker |
| Formula | C14H21NO6 |
| Molecular Weight | 299.32 |
| SMILES | O=C(O)CCCCCCCCC(=O)ON1C(=O)CCC1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.