Fig. 1 · Structure
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10-Aminodecanoic acid
PROTAC Linker
10-Aminodecanoic acid serves as a versatile PROTAC linker, characterized by its alkane chain that features both terminal carboxylic acid and amine functional groups. This compound plays a crucial role in the synthesis of PROTACs, facilitating the formation of stable amide bonds through interactions with activated NHS esters, carboxylic acids, and carbonyls. Its unique reactive properties enable effective conjugation strategies, making it essential for chemical research in targeted protein degradation and related applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 13108-19-5 |
| Applications | PROTAC Linker |
| Formula | C10H21NO2 |
| Molecular Weight | 187.28 |
| SMILES | C(CCCCC(=O)O)CCCCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.