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10-(Diethoxy-phosphoryl)-decyl-phosphonic acid

PROTAC Linker

[10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid is a versatile alkyl chain-based linker designed for PROTAC (Proteolysis Targeting Chimeras) development. Its unique chemical structure enables efficient conjugation to target proteins, facilitating the targeted degradation of specific cellular proteins. This compound serves as a critical building block in the synthesis of PROTACs, aiding in the advancement of therapeutic strategies in drug discovery and cellular biology research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1446282-24-1
Applications	PROTAC Linker
Formula	C₁₄H₃₂O₆P₂
Molecular Weight	358.35
SMILES	OP(CCCCCCCCCCP(OCC)(OCC)=O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.