Fig. 1 · Structure
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10-Formylfolic acid
Dihydrofolate Reductase Inhibitor
10-Formylfolic acid is a potent inhibitor of dihydrofolate reductase, an enzyme critical in the folate metabolic pathway. This compound has been shown to exhibit significant biological activity, making it a valuable tool in cancer research. Its role as a potential early indicator of leukemia highlights its importance in diagnostic applications and therapeutic investigations targeting folate-dependent processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 134-05-4 |
| Applications | Dihydrofolate Reductase Inhibitor |
| Formula | C20H19N7O7 |
| Molecular Weight | 469.41 |
| SMILES | O=C(O)[C@@H](NC(C1=CC=C(N(C=O)CC2=NC3=C(N=C2)N=C(N)NC3=O)C=C1)=O)CCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.