Fig. 1 · Structure

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11R-CaN-AID

Calcineurin Inhibitor

11R-CaN-AID is a potent inhibitor of calcineurin, a calcium-calmodulin-dependent phosphatase. It effectively penetrates cell membranes, making it suitable for in vitro studies of calcineurin signaling pathways. This reagent is valuable for research applications investigating the role of calcineurin in processes such as T-cell activation and cardiac hypertrophy.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 650603-03-5
Applications Calcineurin Inhibitor
Formula C135H248N70O34S2
Molecular Weight 3459.99
SMILES
C(=O)(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CC(O)=O)=O)CO)=O)CCC2)CCSC)=O)C)=O)CC(O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC1)[C@H]3N(C([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)=O)=O)CCCNC(=N)N)=O)CCSC)=O)C)=O)CCC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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