Fig. 1 · Structure
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11R-VIVIT
NFAT Inhibitor
11R-VIVIT is a cell-permeable inhibitor targeting the nuclear factor of activated T cells (NFAT). It demonstrates key biological activity by modulating NFAT signaling pathways, making it valuable for research into podocyte function and diabetic nephropathy. This compound facilitates the exploration of NFAT's role in various cellular processes and disease models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 592517-80-1 |
| Applications | NFAT Inhibitor |
| Formula | C147H259N67O36S |
| Molecular Weight | 3573.15 |
| Synonyms | Cell permeable NFAT inhibitor |
| SMILES | C([C@@H](NC(=O)[C@H]1N(C(CNC([C@@H](NC([C@@H](NC(CNC(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)=O)=O)CCSC)=O)C)=O)=O)CCC1)CC2=CN=CN2)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(=O)N4[C@H](C(N[C@@H](CC5=CN=CN5)C(N[C@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)CCC(O)=O)=O)=O)CCC4)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)C(C)C)=O)[C@H](CC)C)=O)[C@H](C)C)=O)CCC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.