Fig. 1 · Structure
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12(S)-HPETE
Cat. No.
A64068
CAS
71774-10-2
12-Lipoxygenase Metabolite
12(S)-HPETE, a metabolite of 12-lipoxygenase, plays a crucial role in regulating vascular tone. It induces the expression of c-Fos and c-Jun proteins while increasing activating protein 1 (AP-1) activity in vascular smooth muscle cells. This compound may be pivotal in vasomotor regulation, influencing interactions between endothelial cells and adjacent blood cells. 12(S)-HPETE is useful for investigating cerebrovascular tension in various research contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 71774-10-2 |
| Applications | 12-Lipoxygenase Metabolite |
| Formula | C20H32O4 |
| Molecular Weight | 336.47 |
| SMILES | CCCCC/C=C\C[C@H](OO)/C=C/C=C\C/C=C\CCCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.