Fig. 1 · Structure
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12-(tert-Butoxy)-12-oxododecanoic acid
PROTAC Linker
12-(tert-Butoxy)-12-oxododecanoic acid serves as a versatile PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound is crucial for achieving targeted protein degradation by connecting the target protein to an E3 ubiquitin ligase. Its unique structural features enhance the stability and efficacy of PROTACs, making it an essential tool for chemical biology and therapeutic research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 234081-98-2 |
| Applications | PROTAC Linker |
| Formula | C16H30O4 |
| Molecular Weight | 286.41 |
| SMILES | O=C(O)CCCCCCCCCCC(=O)OC(C)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.