12α-Hydroxysteroid dehydrogenase from Bacillus sphaericus is an NAD-dependent enzyme that primarily targets bile acids, exhibiting activity on both bound and unbound forms. This enzyme plays a pivotal role in the metabolism of 12α-hydroxy bile acids and can be utilized to quantify their concentration in serum samples. Its application is significant in studies of bile acid metabolism and related pathophysiological conditions.
12α-Hydroxysteroid dehydrogenase from Bacillus sphaericus is an NAD-dependent enzyme that primarily targets bile acids, exhibiting activity on both bound and unbound forms. This enzyme plays a pivotal role in the metabolism of 12α-hydroxy bile acids and can be utilized to quantify their concentration in serum samples. Its application is significant in studies of bile acid metabolism and related pathophysiological conditions.
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