Fig. 1 · Structure
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(+/-)13-HODE cholesteryl ester
Cat. No.
A74487
CAS
167354-91-8
Endogenous Metabolite
(+/-) 13-HODE cholesteryl ester is an endogenous metabolite derived from atherosclerotic lesions, produced through the Cu2+-catalyzed oxidation of low-density lipoprotein (LDL). It is synthesized by the action of lipoxygenase enzymes, particularly 15-lipoxygenase from rabbit reticulocytes and human monocytes, acting on cholesteryl linoleate, a key component of LDL. This compound is essential for studying lipid metabolism and the pathophysiological mechanisms involved in atherosclerosis and related cardiovascular conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 167354-91-8 |
| Applications | Endogenous Metabolite |
| Formula | C₄₅H₇₆O₃ |
| Molecular Weight | 665.08 |
| SMILES | CCCCCC(O)/C=C/C=C\CCCCCCCC(O[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@@]4(C)[C@](CC[C@]4([H])[C@@H](CCCC(C)C)C)([H])[C@]3([H])CC=C2C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.