Fig. 1 · Structure

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13-Hydroxyisobakuchiol

Cat. No. A67467 CAS 178765-49-6

Monoamine Transporter Inhibitor

13-Hydroxyisobakuchiol is a selective inhibitor of monoamine transporters, primarily targeting the dopamine transporter (DAT) and norepinephrine transporter (NET) with IC50 values of 0.58 μM and 0.69 μM, respectively. In contrast, it exhibits significantly lower affinity for the serotonin transporter (SERT), with an IC50 of 312.02 μM. This compound is valuable for research applications related to neurodegenerative diseases, including Parkinson's disease, and mood disorders such as depression.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 178765-49-6
Applications Monoamine Transporter Inhibitor
Formula C18H24O2
Molecular Weight 272.38
Synonyms Delta3,2-Hydroxylbakuchiol
SMILES
OC1=CC=C(/C=C/[C@](C)(C=C)C/C=C/C(C)(O)C)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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