Fig. 1 · Structure
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14-((2,5-Dioxopyrrolidin-1-yl)oxy)-14-oxotetradecanoic acid
PROTAC Linker
14-((2,5-Dioxopyrrolidin-1-yl)oxy)-14-oxotetradecanoic acid serves as a PROTAC linker, facilitating the development of PROTAC (Proteolysis Targeting Chimera) molecules. This compound plays a critical role in achieving targeted protein degradation, enabling researchers to explore mechanisms of action by selectively degrading proteins of interest. Its utilization in PROTAC synthesis supports investigations in drug discovery and therapeutic applications aimed at modulating protein levels within various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 146004-82-2 |
| Applications | PROTAC Linker |
| Formula | C18H29NO6 |
| Molecular Weight | 355.43 |
| SMILES | O=C(O)CCCCCCCCCCCCC(=O)ON1C(=O)CCC1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.