Fig. 1 · Structure
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14-Anhydrodigitoxigenin
Na+/K+-ATPase Inhibitor
14-Anhydrodigitoxigenin is a potent inhibitor of Na+/K+-ATPase, a crucial enzyme involved in maintaining ion gradients across cell membranes. Derived from the leaves of Acokanthera oblongifolia, this cardenolide exhibits significant biological activity relevant to cardiovascular research and cellular physiology. Its application in studies of cardiac function and electrolyte balance makes it a valuable reagent for investigating the roles of Na+/K+-ATPase in various physiological and pathological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 4321-20-4 |
| Applications | Na+/K+-ATPase Inhibitor |
| Formula | C23H32O3 |
| Molecular Weight | 356.50 |
| SMILES | C[C@]12C([C@@]3([H])[C@]([C@@]4([C@](C[C@H](CC4)O)([H])CC3)C)([H])CC2)=CC[C@]1([H])C(CO5)=CC5=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.