Fig. 1 · Structure
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14-Hydroxytetradecanoic acid
PROTAC Linker
14-Hydroxytetradecanoic acid is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates targeted protein degradation, an essential mechanism in the study of proteostasis and disease modulation. Its role in linking ligands to E3 ligase components makes it a valuable tool for researchers investigating therapeutic strategies in cancer and other diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 17278-74-9 |
| Applications | PROTAC Linker |
| Formula | C14H28O3 |
| Molecular Weight | 244.38 |
| SMILES | O=C(O)CCCCCCCCCCCCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.