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142I5

Apoptosis Antagonist

142I5 is a potent apoptosis antagonist targeting ML-IAP with a Lys-covalent inhibitory mechanism. It exhibits a significant inhibitory activity with an IC50 value of 11 nM, making it an effective tool for studying apoptotic pathways. This compound is ideal for research applications focused on cancer biology and therapeutic interventions related to apoptosis modulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	2865171-75-9
Applications	Apoptosis Antagonist
Formula	C₂₉H₃₆FN₅O₇S
Molecular Weight	617.69
SMILES	O=S(C1=CC=C(OC)C(C(NC[C@H](NC([C@@H](NC)C)=O)C(N2[C@H](C(N[C@@H]3CCC4=C3C=CC=C4)=O)CCC2)=O)=O)=C1)(F)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.