Fig. 1 · Structure
Documents & Downloads
(±)15-HEDE
Cat. No.
A76445
CAS
77159-57-0
Lipoxygenase Inhibitor
(±)15-HEDE is a racemic mixture comprised of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE, derived from eicosadienoic acid within macrophages. This compound acts as a selective inhibitor of 5-lipoxygenase (5-LO) with an IC50 value of 35 μM. 15-HEDE is utilized in research to investigate lipoxygenase pathways and their implications in inflammatory processes. Its inhibitory effects on 5-LO make it a valuable tool for studying the modulation of leukotriene biosynthesis and related biological activities.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 77159-57-0 |
| Applications | Lipoxygenase Inhibitor |
| Formula | C20H36O3 |
| Molecular Weight | 324.50 |
| SMILES | CCCCCC(O)/C=C/C=C\CCCCCCCCCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.