Fig. 1 · Structure
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15-LOX-1 inhibitor 1
Cat. No.
A76413
CAS
2349374-37-2
15-LOX-1 Inhibitor
15-LOX-1 inhibitor 1 is a selective inhibitor of 15-lipoxygenase-1 (15-LOX-1) with an IC50 value of 0.19 μM. This compound demonstrates protective effects on macrophages against cytotoxicity induced by lipopolysaccharide, while also inhibiting nitric oxide formation and lipid peroxidation. With its ability to modulate inflammatory pathways, 15-LOX-1 inhibitor 1 is valuable for research applications focused on inflammation and oxidative stress.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2349374-37-2 |
| Applications | 15-LOX-1 Inhibitor |
| Formula | C22H21ClN2O4 |
| Molecular Weight | 412.87 |
| SMILES | O=C(C(N1)=C(/C=C/C(NCC2=CC=CC=C2OC)=O)C3=C1C=C(Cl)C=C3)OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.