Fig. 1 · Structure
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16(S)-Iloprost
Stereoisomer
16(S)-Iloprost is a stereoisomer of Iloprost, primarily acting as a potent inhibitor of platelet aggregation. It demonstrates significant biological activity with an IC50 value of 3.5 nM, indicating its effectiveness in reducing platelet aggregation. Additionally, it exhibits balanced binding to platelet membrane receptors, with a dissociation constant (Kd) of 13.4 nM. This compound is utilized in research applications focusing on cardiovascular diseases and hemostatic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 74843-14-4 |
| Applications | Stereoisomer |
| Formula | C22H32O4 |
| Molecular Weight | 360.49 |
| SMILES | O[C@@H]1C[C@@H]([C@@H]([C@H]1/C=C/[C@H]([C@H](CC#CC)C)O)C/2)CC2=C/CCCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.