Fig. 1 · Structure
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17-HETE
Cat. No.
A67533
CAS
128914-47-6
CYP1B1 Activator
17-HETE is a metabolite of arachidonic acid produced via cytochrome P-450 pathways, comprising the 17R-HETE and 17S-HETE enantiomers. It acts as an allosteric activator of cytochrome P450 1B1 and an ATPase inhibitor, thereby playing a significant role in the induction of cardiac hypertrophy. This compound is valuable for research in cardiovascular biology and cytochrome P450 enzyme activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 128914-47-6 |
| Applications | CYP1B1 Activator |
| Formula | C20H32O3 |
| Molecular Weight | 320.47 |
| SMILES | CCCC(C/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.