Fig. 1 · Structure
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17-Phenyl trinor PGF2α isopropyl ester
Prostaglandin Receptor
17-Phenyl trinor PGF2α isopropyl ester is a synthetic analog of F-series prostaglandins targeting the FP receptor. It exhibits potent agonistic activity, pivotal for reducing intraocular pressure (IOP), making it relevant in glaucoma research. In comparative studies, this compound has demonstrated significant IOP-lowering effects in animal models, outperforming other analogs while eliciting a pronounced irritant response. Its properties are key in exploring therapeutic options for ocular hypertension.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 130209-76-6 |
| Applications | Prostaglandin Receptor |
| Formula | C26H38O5 |
| Molecular Weight | 430.58 |
| SMILES | O=C(OC(C)C)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C[C@@H]1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.