Fig. 1 · Structure
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19(S)-HETE
IP Receptor Agonist
19(S)-HETE is an arachidonic acid metabolite synthesized by cytochrome P450 enzymes and serves as a full orthosteric agonist of the prostacyclin (IP) receptor, exhibiting an EC50 value of 567 nM. Its biological activity includes inhibition of platelet activation and promotion of vascular relaxation. This compound is utilized in research exploring cardiovascular functions and the modulation of platelet activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 115461-40-0 |
| Applications | IP Receptor Agonist |
| Formula | C20H32O3 |
| Molecular Weight | 320.47 |
| SMILES | C[C@H](O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.