Fig. 1 · Structure
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(1R,2S)-Deoxy-PR280
Dihydroceramide Desaturase Inhibitor
(1R,2S)-Deoxy-PR280 is a competitive inhibitor of dihydroceramide desaturase, exhibiting an inhibition constant (Ki) of 6 µM. This compound is essential for studying sphingolipid metabolism and related signaling pathways. Its inhibitory action provides valuable insights into cellular processes, making it applicable in research on cancer, neurodegeneration, and metabolic diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 649767-83-9 |
| Applications | Dihydroceramide Desaturase Inhibitor |
| Formula | C27H51NO3 |
| Molecular Weight | 437.71 |
| SMILES | [C@H]([C@H](NC(CCCCCCC)=O)CO)(O)C1=C(CCCCCCCCCCCCC)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.