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Biological Activity
(1S,2S,3R)-DT-061 is an enantiomer of DT-061. DT-061 is an orally bioavailable activator of protein phosphatase 2A (PP2A) and could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.21 mL | 96.06 mL | 192.12 mL |
| 0.5 mM | 3.84 mL | 19.21 mL | 38.42 mL |
| 1 mM | 1.92 mL | 9.61 mL | 19.21 mL |
| 5 mM | 0.38 mL | 1.92 mL | 3.84 mL |
*The above data is based on the productmolecular weight 520.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21701 |
|---|---|
| Actions | Activator |
| CAS No. | 1809427-20-0 |
| Formula | C25H23F3N2O5S |
| M. Wt | 520.52 |
| Purity | >98% |
| Synonyms | DT061, DT 061 |
| SMILES | O=S(C1=CC=C(OC(F)(F)F)C=C1)(N[[email protected]@H]2[[email protected]@H](O)[[email protected]](N3C4=C(C=CC=C4)OC5=CC=CC=C35)CCC2)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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