Fig. 1 · Structure
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2-(2-Bromoethyl)-1,3-dioxolane
PROTAC Linker
2-(2-Bromoethyl)-1,3-dioxolane serves as a versatile PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). Its structure enables efficient coupling of target proteins to E3 ligases, playing a crucial role in modulating protein degradation pathways. This compound is essential for researchers aiming to explore targeted protein degradation and its therapeutic implications in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 18742-02-4 |
| Applications | PROTAC Linker |
| Formula | C5H9BrO2 |
| Molecular Weight | 181.03 |
| SMILES | BrCCC1OCCO1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.