Fig. 1 · Structure

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2-(4-(Aminomethyl)piperidin-1-yl)acetonitrile dihydrochloride

PROTAC Linker

2-(4-(Aminomethyl)piperidin-1-yl)acetonitrile dihydrochloride is a PROTAC linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). It facilitates the formation of compounds that selectively degrade specific proteins by harnessing the ubiquitin-proteasome system. This reagent is essential for researchers developing novel therapeutic modalities that utilize protein degradation pathways.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1354953-43-7
Applications PROTAC Linker
Formula C8H17Cl2N3
Molecular Weight 226.15
SMILES
N#CCN1CCC(CC1)CN.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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