Fig. 1 · Structure
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2-(4-Cyanophenyl)acetic acid
PROTAC Linker
2-(4-Cyanophenyl)acetic acid functions as a versatile PROTAC linker, integral to the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the formation of heterobifunctional molecules that induce ubiquitin-mediated degradation of target proteins, enabling selective modulation of protein levels. Its application in chemical biology research supports the development of targeted therapies and enhances investigations into protein degradation pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 5462-71-5 |
| Applications | PROTAC Linker |
| Formula | C9H7NO2 |
| Molecular Weight | 161.16 |
| SMILES | N#CC1=CC=C(C=C1)CC(=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.