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2-ACC

D46A Activator

2-ACC (2-α-Carboxy cholestanol) is identified as a D46A activator of the Sonic Hedgehog protein, exhibiting an EC50 of approximately 5 μM. This compound is essential for studies involving hedgehog signaling pathways and can be utilized in research focused on developmental biology and cancer therapeutics. Its activation of the D46A mutant provides valuable insights into protein interactions and cellular responses mediated by the Sonic Hedgehog pathway.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Activator
CAS Number	3091880-01-9
Applications	D46A Activator
Formula	C₂₈H₄₈O₃
Molecular Weight	432.68
Synonyms	2-α-Carboxy cholestanol
SMILES	C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@H]([C@@H](C2)C(O)=O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.