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2-Acetoxyacorenone

AChE/BACE1 Inhibitor

2-Acetoxyacorenone is a sesquiterpenoid that functions as a potent inhibitor of acetylcholinesterase (AChE) and β-secretase 1 (BACE1). Isolated from the rhizome of Acorus tatarinowii, this compound exhibits significant biological activity relevant to the modulation of cholinergic signaling and amyloid precursor protein processing. It serves as a valuable tool in Alzheimer's disease research, allowing for investigations into therapeutic strategies targeting these key enzymes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	185154-95-4
Applications	AChE/BACE1 Inhibitor
Formula	C₁₇H₂₆O₃
Molecular Weight	278.39
SMILES	CC([C@H]1[C@@]2(CC(C(C)=CC2)=O)[C@H](C[C@H]1OC(C)=O)C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.