Fig. 1 · Structure
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2-(Aminooxy)ethanamine dihydrochloride
PROTAC Linker
2-(Aminooxy)ethanamine dihydrochloride serves as a linker for the development of PROTACs (Proteolysis Targeting Chimeras), facilitating targeted protein degradation. This compound enables the synthesis of novel PROTACs by providing a unique connection between the ligand and the E3 ligase recruiter. Its application is crucial in studying protein function and regulation, with potential implications in therapeutic interventions for various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 37866-45-8 |
| Applications | PROTAC Linker |
| Formula | C2H10Cl2N2O |
| Molecular Weight | 149.02 |
| SMILES | NOCCN.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.