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2-(Biotin-amido)-1,3-bis-(C1-PEG1-acid)

PROTAC Linker

2-(Biotin-amido)-1,3-bis-(C1-PEG1-acid) functions as a PEG-based linker for PROTAC (proteolysis-targeting chimera) technology. This compound facilitates the conjugation of biotin to target proteins, enabling the development of targeted protein degradation systems. Its use is essential in synthesizing novel PROTACs for research applications aimed at understanding protein functionality and therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2086689-02-1
Applications	PROTAC Linker
Formula	C₁₉H₃₁N₃O₈S
Molecular Weight	461.53
SMILES	O=C1N[C@]2(CS[C@H]([C@]2(N1)[H])CCCCC(NC(COCCC(O)=O)COCCC(O)=O)=O)[H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.