Fig. 1 · Structure
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2-Bromo-4'-hydroxyacetophenone
PTP1B Inhibitor
2-Bromo-4'-hydroxyacetophenone functions as a potent inhibitor of PTP1B, exhibiting a Ki value of 42 μM. This compound serves as an important intermediate in the synthesis of LXRα/β antagonists. Additionally, 2-Bromo-4'-hydroxyacetophenone is utilized in research focused on hematological diseases, providing valuable insights into therapeutic pathways. Its distinctive chemical properties make it a useful tool for investigating various biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2491-38-5 |
| Applications | PTP1B Inhibitor |
| Formula | C8H7BrO2 |
| Molecular Weight | 215.05 |
| SMILES | OC1=CC=C(C(CBr)=O)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.