Fig. 1 · Structure
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2-Chloro-1,4-naphthoquinone
Reactive Intermediate
2-Chloro-1,4-naphthoquinone is a reactive intermediate with potent cytotoxic properties, functioning as a vitamin K-dependent carboxylation antagonist. It exhibits an IC50 value of 146 μM, demonstrating its effectiveness in inhibiting enzymatic processes reliant on vitamin K. This compound is valuable for biochemical research focused on understanding carboxylation mechanisms and exploring potential therapeutic applications in cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1010-60-2 |
| Applications | Reactive Intermediate |
| Formula | C10H5ClO2 |
| Molecular Weight | 192.60 |
| SMILES | O=C1C(Cl)=CC(C2=C1C=CC=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.