Fig. 1 · Structure

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2-Chloro-ATP

Guanylate Cyclase Inhibitor

2-Chloro-ATP functions as a soluble guanylate cyclase inhibitor, impacting intracellular signaling pathways. This compound elevates intracellular calcium concentrations at low concentrations, utilizing a mechanism that does not rely on inositol phosphate production. It is valuable for studies investigating the role of guanylate cyclase in various physiological and pathological conditions. Researchers can utilize 2-Chloro-ATP to understand the modulation of calcium signaling in cellular processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 49564-60-5
Applications Guanylate Cyclase Inhibitor
Formula C10H15ClN5O13P3
Molecular Weight 541.63
SMILES
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=C(Cl)N=C3N)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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