2-D08

Name: 2-D08
Brand: Adooq Bioscience
SKU: A16852
Rating: 5 (288 reviews)

Catalog No.: A16852

SUMO inhibitor

2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation. It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET, KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays.

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Grouped product items
Size	Price	Stock
5mg	$45.00	In stock
10mg	$80.00	In stock
25mg	$180.00	In stock
50mg	$290.00	In stock
100mg	$530.00	In stock
*10mM 1mL in DMSO**	$50.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation. It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET, KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays.

Product Information

Catalog Num	A16852
Formula	C15H10O5
Molecular Weight	270.24
CAS Number	144707-18-6
SMILES	O=C1C=C(C2=CC=C(O)C(O)=C2O)OC3=CC=CC=C13
Synonyms	2D08
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	46 mg/mL (170.22 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	37 mL	185.02 mL	370.04 mL
0.5 mM	7.4 mL	37 mL	74.01 mL
1 mM	3.7 mL	18.5 mL	37 mL
5 mM	0.74 mL	3.7 mL	7.4 mL

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂