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2’-Deoxy-2’-fluoro-5-methyl-4’-thio-a-D-arabino uridine

Purine Nucleoside Analog

2’-Deoxy-2’-fluoro-5-methyl-4’-thio-a-D-arabino uridine is a purine nucleoside analog designed to interfere with nucleic acid metabolism. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. This compound is valuable for cancer research, particularly in studying the mechanisms of tumor cell proliferation and potential therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	294868-24-9
Applications	Purine Nucleoside Analog
Formula	C₁₀H₁₃FN₂O₄S
Molecular Weight	276.28
SMILES	OC[C@@H]1[C@@H](O)[C@H](F)[C@@H](N2C=C(C)C(NC2=O)=O)S1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.