Fig. 1 · Structure
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2′-Deoxy-β-L-uridine
Nucledside Analogue
2'-Deoxy-β-L-uridine is a nucleoside analogue that serves as a specific substrate for the viral enzyme, demonstrating no stereospecificity against herpes simplex virus type 1 (HSV1) thymidine kinase. This compound exhibits antiviral activity through the interaction of its 5'-triphosphate form with viral DNA polymerase, thereby inhibiting viral replication. It is a valuable tool in studying HSV1 and other viral infections, as well as in developing antiviral therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 31501-19-6 |
| Applications | Nucledside Analogue |
| Formula | C9H12N2O5 |
| Molecular Weight | 228.20 |
| SMILES | O=C(NC(C=C1)=O)N1[C@@H]2C[C@@H](O)[C@H](CO)O2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.