2'-Deoxyadenosine-13C10,15N5 is a stable isotope-labeled form of 2'-Deoxyadenosine that features 13C and 15N isotopes. This nucleoside is known to inhibit glucose-stimulated insulin release and attenuates increases in cyclic AMP (cAMP) accumulation in islet cells. Additionally, 2'-Deoxyadenosine activates caspase-3, promoting apoptosis, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity. This compound also exhibits growth inhibitory effects on various cell types and demonstrates anticancer activity against colon cancer, making it a valuable tool for biochemical and pharmaceutical research.
2'-Deoxyadenosine-13C10,15N5 is a stable isotope-labeled form of 2'-Deoxyadenosine that features 13C and 15N isotopes. This nucleoside is known to inhibit glucose-stimulated insulin release and attenuates increases in cyclic AMP (cAMP) accumulation in islet cells. Additionally, 2'-Deoxyadenosine activates caspase-3, promoting apoptosis, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity. This compound also exhibits growth inhibitory effects on various cell types and demonstrates anticancer activity against colon cancer, making it a valuable tool for biochemical and pharmaceutical research.
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