2'-Deoxyadenosine-13C5 monohydrate is a stable isotope-labeled analog of 2'-deoxyadenosine, primarily targeting cellular pathways involved in insulin regulation. This compound inhibits glucose-stimulated insulin release and reduces islet cyclic AMP (cAMP) accumulation. Additionally, it activates caspase-3, promoting apoptotic processes, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity. 2'-Deoxyadenosine has demonstrated cytotoxic effects on various cancer cell lines, including those associated with colon cancer, making it a valuable tool for research in cancer biology and metabolic regulation.
2'-Deoxyadenosine-13C5 monohydrate is a stable isotope-labeled analog of 2'-deoxyadenosine, primarily targeting cellular pathways involved in insulin regulation. This compound inhibits glucose-stimulated insulin release and reduces islet cyclic AMP (cAMP) accumulation. Additionally, it activates caspase-3, promoting apoptotic processes, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity. 2'-Deoxyadenosine has demonstrated cytotoxic effects on various cancer cell lines, including those associated with colon cancer, making it a valuable tool for research in cancer biology and metabolic regulation.
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